Article
Solution structure of human IL-13 and implication for receptor binding.
Journal of molecular biology - 29 Jun 2001
Moy F J, Diblasio E, Wilhelm J, Powers R
Abstract excerpt
Interleukin-13 has been implicated as a key factor in asthma, allergy, atopy and inflammatory response, establishing the protein as a valuable therapeutic target. The high-resolution solution structure of human IL-13 has been determined by multidimensional NMR. The resulting structure is consistent with previous short-chain left-handed four-helix bundles, where a significant similarity in the folding topology...
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