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Article

Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction.

The EMBO journal - 1 Jul 1993

Zurawski S M, Vega F, Huyghe B, Zurawski G

Abstract excerpt

Interleukin-4 (IL-4) and interleukin-13 (IL-13) are two cytokines that are secreted by activated T cells and have similar effects on monocytes and B cells. We describe a mutant form of human interleukin-4 (hIL-4) that competitively antagonizes both hIL-4 and human interleukin-13 (hIL-13). The amino acid sequences of IL-4 and IL-13 are approximately 30% homologous and circular dichroism (CD) spectroscopy shows...

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Identifiers

PMID: 8101483
DOI: 10.1002/j.1460-2075.1993.tb05927.x
PMCID: PMC413514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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