Article
Multilocus analysis of extracellular putative virulence proteins made by group A Streptococcus: population genetics, human serologic response, and gene transcription.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2001
Reid S D, Green N M, Buss J K, Lei B, Musser J M
Abstract excerpt
Species of pathogenic microbes are composed of an array of evolutionarily distinct chromosomal genotypes characterized by diversity in gene content and sequence (allelic variation). The occurrence of substantial genetic diversity has hindered progress in developing a comprehensive understanding of the molecular basis of virulence and new therapeutics such as vaccines. To provide new information that bears on...
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