Article
Evolution of diversity in epidemics revealed by analysis of the human bacterial pathogen group A Streptococcus.
Epidemics - 1 Sept 2011
Carroll Ronan K, Beres Stephen B, Sitkiewicz Izabela, Peterson Leif, Matsunami Risë K, Engler David A, Flores Anthony R, Sumby Paul, Musser James M
Abstract excerpt
Advancements in high-throughput, high-volume data generating techniques increasingly present us with opportunities to probe new areas of biology. In this work we assessed the extent to which four closely related and genetically representative strains of group A Streptococcus causing epidemic disease have differentiated from one another. Comparative genome sequencing, expression microarray analysis, and proteomic...
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