Article
Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategies.
The American journal of pathology - 1 Feb 2005
Graham Morag R, Virtaneva Kimmo, Porcella Stephen F, Barry William T, Gowen Brian B, Johnson Claire R, Wright Fred A, Musser James M
Abstract excerpt
The molecular basis for bacterial responses to host signals during natural infections is poorly understood. The gram-positive bacterial pathogen group A Streptococcus (GAS) causes human mucosal, skin, and life-threatening systemic infections. During the transition from a throat or skin infection to an invasive infection, GAS must adapt to changing environments and host factors. To better understand how GAS...
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