Article
Identification and characterization of the scl gene encoding a group A Streptococcus extracellular protein virulence factor with similarity to human collagen.
Infection and immunity - 1 Dec 2000
Lukomski S, Nakashima K, Abdi I, Cipriano V J, Ireland R M, Reid S D, Adams G G, Musser J M
Abstract excerpt
Group A Streptococcus (GAS) expresses cell surface proteins that mediate important biological functions such as resistance to phagocytosis, adherence to plasma and extracellular matrix proteins, and degradation of host proteins. An open reading frame encoding a protein of 348 amino acid residues was identified by analysis of the genome sequence available for a serotype M1 strain. The protein has an LPATGE...
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