Variations in the distribution of genes encoding virulence and extracellular proteins in group A streptococcus are largely restricted to 11 genomic loci.

doi:10.1016/j.micinf.2006.11.014

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Article

Variations in the distribution of genes encoding virulence and extracellular proteins in group A streptococcus are largely restricted to 11 genomic loci.

Microbes and infection - 1 Mar 2007

McMillan David J, Geffers Robert, Buer Jan, Vlaminckx Bart J M, Sriprakash Kadaba S, Chhatwal Gursharan S

Abstract excerpt

Group A streptococcus (GAS) is a human pathogen associated with a wide range of human diseases that vary in symptoms and clinical severity. In this report we describe the use of a targeted low density array representing genes encoding classical virulence factors, purported virulence factors and other extracellular proteins to examine differences in the genetic profiles of 68 clinical GAS isolates. Of the 226...

Topics

Antigens, Bacterial
Bacterial Outer Membrane Proteins
Bacterial Proteins
Carrier Proteins
Chromosome Mapping
Genetic Variation
Genome, Bacterial
Humans
Interspersed Repetitive Sequences
Oligonucleotide Array Sequence Analysis
Polymerase Chain Reaction
Streptococcus Phages

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Streptococcus pyogenes

Virulence

Virulence Factors

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Open in PubMed

Identifiers

PMID: 17307378
DOI: 10.1016/j.micinf.2006.11.014

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