Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paraoxonase 1 192 Gln/Arg gene polymorphism and cerebrovascular disease: interaction with type 2 diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 2001

Koch M, Hering S, Barth C, Ehren M, Enderle M D, Pfohl M

Abstract excerpt

Paraoxonase 1 (PON1) is an HDL-associated enzyme which protects HDL and LDL particles from lipid peroxidation. Its enzymatic serum activity varies 10-40-fold between individuals, and its biallelic gene polymorphism at codon 192 (glutamine-->arginine, Gln/Arg) has been associated with coronary artery disease in diabetic patients. To evaluate the role of this PON1 gene polymorphism in cerebrovascular disease, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginine
Share to Aryldialkylphosphatase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cerebrovascular Disorders

Share to Diabetes Mellitus, Type 2

Share to Esterases

Share to Glutamine

Share to Odds Ratio

Share to Smoking

Source

Identifiers

PMID: 11409295
DOI: 10.1055/s-2001-14836

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paraoxonase 1 192 Gln/Arg gene polymorphism and cerebrovascular disease: interaction with type 2 diabetes.PMID 11409295Read ↗

Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.Semantic proximity Read ↗

The influence of PON1 192 polymorphism on endothelial function in diabetic subjects with or without hypertension.Semantic proximity Read ↗

Gln-Arg192 polymorphism of paraoxonase 1 is associated with carotid intima-media thickness in patients of type 2 diabetes mellitus of Chinese.Semantic proximity Read ↗

Risk of myocardial infarction associated with Gln/Arg 192 polymorphism in the human paraoxonase gene and diabetes mellitus. The REGICOR Investigators.Semantic proximity Read ↗

Paraoxonase 192 Gln-->Arg polymorphism: an independent risk factor for nonfatal arterial ischemic stroke among young adults.Semantic proximity Read ↗

Paraoxonase 1 Gln/Arg polymorphism is associated with the risk of microangiopathy in Type 2 diabetes mellitus.Semantic proximity Read ↗

The gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in italian patients.Semantic proximity Read ↗

Influence of the human paraoxonase polymorphism (PON1 192) on the carotid-wall thickening in a healthy population.Semantic proximity Read ↗

The Arg allele in position 192 of PON1 is associated with carotid atherosclerosis in subjects with elevated HDLs.Semantic proximity Read ↗

The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease.Semantic proximity Read ↗

Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes.Semantic proximity Read ↗

Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1(192) or PON1(55) genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.