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Article

Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.

Diabetes - 1 Mar 1999

Pfohl M, Koch M, Enderle M D, Kühn R, Füllhase J, Karsch K R, Häring H U

Abstract excerpt

Paraoxonase is an HDL-associated enzyme implicated in the pathogenesis of atherosclerosis by protecting lipoproteins against peroxidation. Its biallelic gene polymorphism at codon 192 (glutamine/arginine) has been associated with coronary artery disease (CAD). To further evaluate the role of this paraoxonase gene polymorphism for CAD in type 2 diabetes, we determined the paraoxonase genotype in 288 type 2...

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Source

Identifiers

PMID: 10078566
DOI: 10.2337/diabetes.48.3.623

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.PMID 10078566Read ↗

Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes.Semantic proximity Read ↗

The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease.Semantic proximity Read ↗

Risk of myocardial infarction associated with Gln/Arg 192 polymorphism in the human paraoxonase gene and diabetes mellitus. The REGICOR Investigators.Semantic proximity Read ↗

Paraoxonase 1 192 Gln/Arg gene polymorphism and cerebrovascular disease: interaction with type 2 diabetes.Semantic proximity Read ↗

Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.Semantic proximity Read ↗

The gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in italian patients.Semantic proximity Read ↗

The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study.Semantic proximity Read ↗

Paraoxonase Polymorphism (Gln192-Arg) Is Associated with Coronary Heart Disease in Japanese Noninsulin-Dependent Diabetes MellitusSemantic proximity Read ↗

A 192Arg variant of the human paraoxonase (HUMPONA) gene polymorphism is associated with an increased risk for coronary artery disease in the Japanese.Semantic proximity Read ↗

Paraoxonase Gln-Arg(192) and Leu-Met(55) gene polymorphisms and enzyme activity in a population with a low rate of coronary heart disease.Semantic proximity Read ↗

The influence of PON1 192 polymorphism on endothelial function in diabetic subjects with or without hypertension.Semantic proximity Read ↗

Gln-Arg192 polymorphism of paraoxonase 1 is associated with carotid intima-media thickness in patients of type 2 diabetes mellitus of Chinese.Semantic proximity Read ↗

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