Article
Cloning and expression of hamster telomerase catalytic subunit cDNA.
International journal of molecular medicine - 1 Jul 2001
Guo W, Okamoto M, Park N H, Lee Y M, Park N H
Abstract excerpt
Topical application of 7,12-dimethylbenz(alpha)-anthracene induces tumors in the hamster cheek pouch. Telomerase activity is increased in the cancer tissues if compared to normal adjacent tissues in both human and hamster oral cancer. In order to achieve a probe and to investigate the putative role of telomerase in oral carcinogenesis using the hamster cheek pouch model, we have cloned the cDNA encoding the...
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