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Article

Regulation of human telomerase in homeostasis and disease.

Nature reviews. Molecular cell biology - 1 Jul 2020

Roake Caitlin M, Artandi Steven E

Abstract excerpt

Telomerase is a ribonucleoprotein complex, the catalytic core of which includes the telomerase reverse transcriptase (TERT) and the non-coding human telomerase RNA (hTR), which serves as a template for the addition of telomeric repeats to chromosome ends. Telomerase expression is restricted in humans to certain cell types, and telomerase levels are tightly controlled in normal conditions. Increased levels of...

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Identifiers

PMID: 32242127
DOI: 10.1038/s41580-020-0234-z
PMCID: PMC7377944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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