Article
Quercetin, E7 and p53 in papillomavirus oncogenic cell transformation.
Carcinogenesis - 1 Jul 2001
Beniston R G, Morgan I M, O'Brien V, Campo M S
Abstract excerpt
Bovine papillomavirus type 4 (BPV-4) infects the upper alimentary canal of cattle causing benign papillomas which can progress to squamous carcinomas in cattle grazing on bracken fern (BF). We have previously shown that quercetin, a well characterized and potent mutagen found in BF, causes cell cycle arrest of primary bovine cells (PalF), but that a single exposure to quercetin can cause full oncogenic...
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