Article
A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Jun 2007
Béringue Vincent, Andréoletti Olivier, Le Dur Annick, Essalmani Rachid, Vilotte Jean-Luc, Lacroux Caroline, Reine Fabienne, Herzog Laëtitia, Biacabé Anne-Gaëlle, Baron Thierry, Caramelli Maria, Casalone Cristina, Laude Hubert
Abstract excerpt
Implementation in Europe of large-scale testing to detect bovine spongiform encephalopathy (BSE)-infected cattle and prevent the transmission of this prion disease to humans has recently led to the discovery of novel types of bovine prions. We characterized atypical isolates called BSE L-type by analyzing their molecular and neuropathological properties during transmission to several mouse lines transgenic for...
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