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Article

A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans.

Genetics - 1 Jun 2001

Klar A J, Srikantha T, Soll D R

Abstract excerpt

Most strains of Candida albicans undergo high frequency phenotypic switching. Strain WO-1 undergoes the white-opaque transition, which involves changes in colony and cellular morphology, gene expression, and virulence. We have hypothesized that the switch event involves heritable changes in chrom...

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Identifiers

PMID: 11404352
DOI: 10.1093/genetics/158.2.919
PMCID: PMC1461676

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11404352-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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