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Article

Identification of important amino acid residues that modulate binding of Escherichia coli GroEL to its various cochaperones.

Genetics - 1 Jun 2001

Klein G, Georgopoulos C

Abstract excerpt

Genetic experiments have shown that the GroEL/GroES chaperone machine of Escherichia coli is absolutely essential, not only for bacterial growth but also for the propagation of many bacteriophages including lambda. The virulent bacteriophages T4 and RB49 are independent of the host GroES function, because they encode their own cochaperone proteins, Gp31 and CocO, respectively. E. coli groEL44 mutant bacteria do...

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Identifiers

PMID: 11404317
DOI: 10.1093/genetics/158.2.507
PMCID: PMC1461677

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of important amino acid residues that modulate binding of Escherichia coli GroEL to its various cochaperones.PMID 11404317Read ↗

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