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Article

Pathogenicity island‐dependent activation of Rho GTPases Rac1 and Cdc42 in <i>Helicobacter pylori</i> infection

1 May 2001

Abstract excerpt

Helicobacter pylori has been identified as the major aetiological agent in the development of chronic gastritis and duodenal ulcer, and it plays a role in the development of gastric carcinoma. Attachment of H. pylori to gastric epithelial cells leads to nuclear and cytoskeletal responses in host cells. Here, we show that Rho GTPases Rac1 and Cdc42 were activated during infection of gastric epithelial cells with...

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PMID: 11401689
DOI: 10.1046/j.1365-2958.2001.02443.x

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