Article
HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes.
Analytical biochemistry - 15 Apr 2001
Gorshkova I I, Rausch J W, Le Grice S F, Crouch R J
Abstract excerpt
HIV-1 reverse transcriptase (HIV-1 RT) is a multifunctional enzyme responsible for converting viral RNA into preintegrative DNA during the early stages of viral infection. DNA polymerase and RNase H activities are required, and several conformationally distinct primer-templates must be accommodat...
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