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Article

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.

Proteins - 1 Jul 2005

Tachedjian G, Radzio J, Sluis-Cremer N

Abstract excerpt

The multifunctional enzyme human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) is a heterodimer composed of a 66-kDa (p66) subunit and a p66-derived 51-kDa (p51) subunit. p66/p51 HIV-1 RT contains 1 functional DNA polymerase and 1 ribonuclease H (RNase H) active site, which both reside in the p66 subunit at spatially distinct regions. In this study, we have investigated the relationship between...

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Identifiers

PMID: 15852304
DOI: 10.1002/prot.20480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.PMID 15852304Read ↗

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