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Article

Linkage of the Human Inducible Nitric Oxide Synthase Gene to Type 1 Diabetes<sup>1</sup>

1 Jun 2001

Abstract excerpt

Exposure of human pancreatic islets to a mixture of cytokines induces expression of the inducible nitric oxide synthase (iNOS), impairs beta-cell function, and induces apoptosis. We performed a mutational scanning of all 27 exons of the human NOS2 gene and linkage transmission disequilibrium testing of identified NOS2 polymorphisms in a Danish nationwide type 1 diabetes mellitus (IDDM) family collection....

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Identifiers

PMID: 11397889
DOI: 10.1210/jcem.86.6.7559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Linkage of the Human Inducible Nitric Oxide Synthase Gene to Type 1 Diabetes<sup>1</sup>PMID 11397889Read ↗

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