Article
No linkage of P187S polymorphism in NAD(P)H: quinone oxidoreductase (NQO1/DIA4) and type 1 diabetes in the Danish population. DIEGG and DSGD. Danish IDDM Epidemiology and Genetics Group and The Danish Study Group of Diabetes in Childhood.
Human mutation - 1 Jan 1999
Kristiansen O P, Larsen Z M, Johannesen J, Nerup J, Mandrup-Poulsen T, Pociot F
Abstract excerpt
Recent genome screening studies have identified novel regions of possible interest for susceptibility to type 1 diabetes. One of these is a 30-35 cM region mapping to 16q22-q24 (D16S515-D16S520), where also the gene encoding NAD(P)H: quinone oxidoreductase (NQO1) maps. Data has suggested associat...
Topics
- Chromosomes, Human, Pair 16
- Denmark
- Diabetes Mellitus, Type 1
- Female
- Genetic Linkage
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Linkage Disequilibrium
- Male
- NAD(P)H Dehydrogenase (Quinone)