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Article

Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study.

Cancer - 15 Apr 2007

Li Chunying, Hu Zhibin, Liu Zhensheng, Wang Li-E, Gershenwald Jeffrey E, Lee Jeffrey E, Prieto Victor G, Duvic Madeleine, Grimm Elizabeth A, Wei Qingyi

Abstract excerpt

BACKGROUND: Nitric oxide (NO) is a multifunctional molecule that is produced by both neuronal NO synthase (nNOS) and inducible NO synthase (iNOS), and the expression of nNOS and iNOS is up-regulated in various cancer cells, including cutaneous melanoma (CM). The authors hypothesized that selected functional single-nucleotide polymorphisms (SNPs) in the nNOS and iNOS genes are associated with the risk of CM....

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Identifiers

PMID: 17328085
DOI: 10.1002/cncr.22582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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