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Article

Role of the CDC25 homology domain of phospholipase Cepsilon in amplification of Rap1-dependent signaling.

The Journal of biological chemistry - 10 Aug 2001

Jin T G, Satoh T, Liao Y, Song C, Gao X, Kariya K, Hu C D, Kataoka T

Abstract excerpt

Phospholipase Cepsilon (PLCepsilon) is a novel class of phosphoinositide-specific PLC characterized by possession of CDC25 homology and Ras/Rap1-associating domains. We and others have shown that human PLCepsilon is translocated from the cytoplasm to the plasma membrane and activated by direct association with Ras at its Ras/Rap1-associating domain. In addition, translocation to the perinuclear region was induced...

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Source

Identifiers

PMID: 11395506
DOI: 10.1074/jbc.M103530200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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