Article
Analysis of the receptor binding domain of Gpa1p, the G(alpha) subunit involved in the yeast pheromone response pathway.
Molecular and cellular biology - 1 May 1997
Kallal L, Kurjan J
Abstract excerpt
The Saccharomyces cerevisiae G protein alpha subunit Gpa1p is involved in the response of both MATa and MAT alpha cells to pheromone. We mutagenized the GPA1 C terminus to characterize the receptor-interacting domain and to investigate the specificity of the interactions with the a- and alpha-fac...
Topics
- Animals
- Blotting, Western
- Cattle
- GTP-Binding Protein alpha Subunits
- GTP-Binding Protein alpha Subunits, Gq-G11
- GTP-Binding Proteins
- Heterotrimeric GTP-Binding Proteins
- Models, Molecular
- Mutagenesis
- Phenotype
- Pheromones