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Article

Pyruvate oxidase contributes to the aerobic growth efficiency of Escherichia coli.

Microbiology (Reading, England) - 1 Jun 2001

Abdel-Hamid Ahmed M, Attwood Margaret M, Guest John R

Abstract excerpt

The metabolic importance of pyruvate oxidase (PoxB), which converts pyruvate directly to acetate and CO(2), was assessed using an isogenic set of genetically engineered strains of Escherichia coli. In a strain lacking the pyruvate dehydrogenase complex (PDHC), PoxB supported acetate-independent aerobic growth when the poxB gene was expressed constitutively or from the IPTG-inducible tac promoter. Using aerobic...

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PMID: 11390679
DOI: 10.1099/00221287-147-6-1483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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