Article
Multipathways for transdifferentiation of human prostate cancer cells into neuroendocrine-like phenotype.
Biochimica et biophysica acta - 28 May 2001
Zelivianski S, Verni M, Moore C, Kondrikov D, Taylor R, Lin M F
Abstract excerpt
The neuroendocrine (NE) cell is a minor cell population in normal human prostate glands. The number of NE cells is increased in advanced hormone-refractory prostate carcinomas (PCA). The mechanism of increased NE cell population in these advanced tumors is poorly understood. We examined molecular mechanisms which may be involved in the regulation of the transdifferentiation process of human PCA cells leading to a...
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