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Article

The neuroendocrine phenotype in prostate cancer: basic and clinical aspects.

Journal of endocrinological investigation - 1 Jan 2005

Mosca A, Berruti A, Russo L, Torta M, Dogliotti L

Abstract excerpt

Most of the conventional adenocarcinomas of the prostate display focal neuroendocrine (NE) differentiation at diagnosis, usually revealed by immunohistochemistry as solitary or clusters of cells, in the context of predominantly exocrine tumors. Even though the biological and clinical significance of NE differentiation in prostate cancer is still to be elucidated, NE phenotype is emerging as an important factor in...

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PMID: 16625864

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