Article
beta-Catenin expression pattern, beta-catenin gene mutations, and microsatellite instability in endometrioid ovarian carcinomas and synchronous endometrial carcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 2001
Moreno-Bueno G, Gamallo C, Pérez-Gallego L, de Mora J C, Suárez A, Palacios J
Abstract excerpt
beta-Catenin gene mutations and microsatellite instability (MI) have been reported in endometrioid ovarian carcinomas. In colon but not endometrial cancer, beta-catenin gene mutations are associated with a replication error phenotype and MI. In this study the authors investigate whether beta-catenin mutations and MI are two independent oncogenic pathways in endometrioid ovarian carcinomas. They also evaluate the...
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