Article
Frequent microsatellite instability in synchronous ovarian and endometrial adenocarcinoma and its usefulness for differential diagnosis.
Human pathology - 1 Dec 2004
Kaneki Eisuke, Oda Yoshinao, Ohishi Yoshihiro, Tamiya Sadafumi, Oda Shinya, Hirakawa Toshio, Nakano Hitoo, Tsuneyoshi Masazumi
Abstract excerpt
Synchronous tumors of the ovary and endometrium are a well-known phenomenon. There are histological criteria for defining double primary tumors or metastasis from one organ to another, but in some cases a precise diagnosis is difficult. In this study we reviewed 17 cases of synchronous ovarian and endometrial adenocarcinoma by previously reported histological criteria and performed a microsatellite analysis,...
Topics
- Adenocarcinoma
- Adult
- Chromosomes, Human, X
- Clone Cells
- DNA, Neoplasm
- Diagnosis, Differential
- Endometrial Neoplasms
- Female
- Humans
- Microsatellite Repeats
- Middle Aged
- Mutation
- Neoplasms, Multiple Primary