Article
Variants in the alpha2A AR adrenergic receptor gene in psychiatric patients.
American journal of medical genetics - 7 Sept 1998
Feng J, Sobell J L, Heston L L, Goldman D, Cook E, Kranzler H R, Gelernter J, Sommer S S
Abstract excerpt
In various studies of psychiatric patients, alterations in adrenergic receptor (AR) expression or function have been suggested. Herein, the alpha2A AR gene was screened in 206 patients with schizophrenia, attention deficit hyperactivity disorder (ADHD), autism, alcohol dependence, or cocaine dependence. The entire coding region was examined for single base pair changes, using restriction endonuclease...
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