Association between serotonin 2A receptor (HTR2A) genetic variations and risk of hypertension in a community-based cohort study.

doi:10.1186/s12881-019-0927-3

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Article

Association between serotonin 2A receptor (HTR2A) genetic variations and risk of hypertension in a community-based cohort study.

BMC medical genetics - 6 Jan 2020

Choi Jung Ran, Jeon Minhee, Koh Sang Baek

Abstract excerpt

BACKGROUND: Hypertension is one of the risk factors for obesity-related cardiovascular diseases. We investigated whether genetic variations in serotonin 2A receptor (HTR2A) were associated with hypertension. METHODS: We carried out a cross-sectional study in cohorts A (Ansan-Ansung cohort, N = 6039) and B (Wonju-Pyengchang cohort, N = 7524). Several genetic variants in HTR2A including rs7330636, rs9590999,...

Topics

Aged
Body Mass Index
Female
Genetic Association Studies
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hypertension

Male

Middle Aged

Polymorphism, Single Nucleotide

Receptor, Serotonin, 5-HT2A

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 31906879
DOI: 10.1186/s12881-019-0927-3
PMCID: PMC6943889

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