Article
Study of HLA class II loci reveals DQB1*03:03:02 as a risk factor for asthma in a Pakistani population.
International journal of immunogenetics - 1 Dec 2022
Saba Nusrat, Raja Ghazala Kaukab, Yusuf Osman, Rehman Sadia, Munir Saeeda, Sajjad Sumaira, Mansoor Atika
Abstract excerpt
Asthma, a chronic inflammatory disorder of the lungs and airways, typically results from a combination of multiple environmental and genetic factors. Human leucocyte antigen (HLA) region on chromosome 6p21 encodes the most highly polymorphic loci in the human genome, encoding genes with central roles in the immune function where HLA loci are strongly associated with various immune-mediated diseases such as...
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