Article
Immunoglobulin V region gene use and structure suggest antigen selection in AIDS-related primary effusion lymphomas.
Leukemia - 1 Jul 1999
Fais F, Gaidano G, Capello D, Gloghini A, Ghiotto F, Roncella S, Carbone A, Chiorazzi N, Ferrarini M
Abstract excerpt
Primary effusion lymphoma (PEL) is a lymphoproliferation of B cells infected by Kaposi's sarcoma-associated herpes-virus/human herpesvirus-8 and reflecting a late stage of B cell differentiation close to plasma cell. Apart from viral infection, the pathogenesis of PEL is currently unclear. The aim of the present study was to investigate the role of antigen stimulation and selection in the evolution of PEL. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
