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Article

Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype.

Molecular microbiology - 1 May 2005

Duffy Michael F, Byrne Timothy J, Elliott Salenna R, Wilson Danny W, Rogerson Stephen J, Beeson James G, Noviyanti Rintis, Brown Graham V

Abstract excerpt

Transcription of the majority of the members of the Plasmodium falciparum var multigene family were analysed in two isolates by a quantitative approach. Both of these isolates had been repeatedly selected for adhesion to chondroitin sulphate A (CSA) and one had also been selected for adhesion to hyaluronic acid (HA). These adhesion phenotypes are expressed by many parasites isolated from placentae and are...

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Identifiers

PMID: 15819631
DOI: 10.1111/j.1365-2958.2005.04577.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype.PMID 15819631Read ↗

Selective upregulation of a single distinctly structured <i>var</i> gene in chondroitin sulphate A‐adhering <i>Plasmodium falciparum</i> involved in pregnancy‐associated malariaSemantic proximity Read ↗

High level of var2csa transcription by Plasmodium falciparum isolated from the placenta.Semantic proximity Read ↗

Transcription of multiple var genes by individual, trophozoite‐stage Plasmodium falciparum cells expressing a chondroitin sulphate A binding phenotypeSemantic proximity Read ↗

Multiple var gene transcripts are expressed in Plasmodium falciparum infected erythrocytes selected for adhesion.Semantic proximity Read ↗

Transcriptome analysis of antigenic variation in Plasmodium falciparum - var silencing is not dependent on antisense RNASemantic proximity Read ↗

VAR2CSA Expression on the Surface of Placenta‐DerivedPlasmodium falciparum–Infected ErythrocytesSemantic proximity Read ↗

A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A.Semantic proximity Read ↗

scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidanceSemantic proximity Read ↗

Cross-Reactive Surface Epitopes on Chondroitin Sulfate A-AdherentPlasmodium falciparum-Infected Erythrocytes Are Associated with Transcription ofvar2csaSemantic proximity Read ↗

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