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Article

Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene.

Molecular and cellular endocrinology - 25 May 2001

Whitfield G K, Remus L S, Jurutka P W, Zitzer H, Oza A K, Dang H T, Haussler C A, Galligan M A, Thatcher M L, Encinas Dominguez C, Haussler M R

Abstract excerpt

The functional significance of two unlinked human vitamin D receptor (hVDR) gene polymorphisms was evaluated in twenty human fibroblast cell lines. Genotypes at both a Fok I restriction site (F/f) in exon II and a singlet (A) repeat in exon IX (L/S) were determined, and relative transcription activities of endogenous hVDR proteins were measured using a transfected, 1,25-dihydroxyvitamin D(3)-responsive reporter...

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PMID: 11377830
DOI: 10.1016/s0303-7207(01)00406-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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