Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional significance of vitamin D receptor FokI polymorphism in human breast cancer cells.

PloS one - 24 Jan 2011

Alimirah Fatouma, Peng Xinjian, Murillo Genoveva, Mehta Rajendra G

Abstract excerpt

BACKGROUND: The FokI vitamin D receptor (VDR) polymorphism results in different translation initiation sites on VDR. In the VDRff variant, initiation of translation occurs at the first ATG site, giving rise to a full length VDR protein of 427 amino acids. Conversely, in the VDRFF variant, translation begins at the second ATG site, resulting in a truncated protein with three less amino acids. Epidemiological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Line, Tumor
Share to Codon, Initiator

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inflammation

Share to Receptors, Calcitriol

Share to Steroid Hydroxylases

Share to Vitamin D

Share to Vitamin D3 24-Hydroxylase

Source

Open in PubMed Open full text

Identifiers

PMID: 21283672
DOI: 10.1371/journal.pone.0016024
PMCID: PMC3025916

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional significance of vitamin D receptor FokI polymorphism in human breast cancer cells.PMID 21283672Read ↗

FokI polymorphism in vitamin D receptor gene and risk of breast cancer among Caucasian women.Semantic proximity Read ↗

FokI polymorphism of Vitamin D receptor gene and deficiency of serum Vitamin D increases the risk of breast cancer in North Indian women.Semantic proximity Read ↗

FokI and BsmI Polymorphisms of the VDR Gene and Breast Cancer RiskSemantic proximity Read ↗

Vitamin D Receptor Gene Polymorphisms and Breast Cancer RiskSemantic proximity Read ↗

Association of the vitamin D receptor FokI gene polymorphism with sex- and non-sex-associated cancers: A meta-analysis.Semantic proximity Read ↗

Associations between vitamin D receptor polymorphisms and breast cancer risk.Semantic proximity Read ↗

The vitamin D receptor gene <i>Fok</i>I polymorphism: Functional impact on the immune systemSemantic proximity Read ↗

The vitamin D receptor gene start codon polymorphism: a functional analysis of FokI variants.Semantic proximity Read ↗

Vitamin D Receptor Gene Polymorphism: Association with Susceptibility to Early-Onset Breast Cancer in Iranian, BRCA1/2-Mutation Carrier and non-carrier Patients.Semantic proximity Read ↗

Serum Vitamin D status and VDR (FokI) polymorphism association study in Pakistani females with breast cancer.Semantic proximity Read ↗

Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.Semantic proximity Read ↗

The impact of vitamin D in breast cancer: genomics, pathways, metabolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.