Influence of rs2228570 on Transcriptional Activation by the Vitamin D Receptor in Human Gingival Fibroblasts and Periodontal Ligament Cells.

doi:10.1902/jop.2017.170030

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Article

Influence of rs2228570 on Transcriptional Activation by the Vitamin D Receptor in Human Gingival Fibroblasts and Periodontal Ligament Cells.

Journal of periodontology - 1 Sept 2017

Liu Kaining, Han Bing, Meng Huanxin, Hou Jianxia

Abstract excerpt

BACKGROUND: rs2228570 is the only known single nucleotide polymorphism of the vitamin D receptor (VDR) that alters the protein structure. VDRs can be distinguished using the restriction endonuclease FokI and accordingly divided into three genotypes: FF, Ff, and ff. Influence of rs2228570 on transcriptional activation by VDRs in human gingival fibroblasts (hGFs) and periodontal ligament cells (hPDLCs) is...

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PMID: 28492361
DOI: 10.1902/jop.2017.170030

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