Article
A review of genetic differences between limited and extensively passaged human cytomegalovirus strains.
Reviews in medical virology - 1 Jan 2000
Prichard M N, Penfold M E, Duke G M, Spaete R R, Kemble G W
Abstract excerpt
The complete genetic content of human cytomegalovirus (HCMV) has been difficult to determine, since most strains studied in the laboratory have been extensively passaged in human fibroblast cultures which can change the genetic content as well as the biological properties of the virus. Approximately 13 kb of novel DNA sequences located near the right edge of the unique long (UL) component of the genome has been...
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