Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169.

The Journal of general virology - 1 Oct 2009

Bradley Amanda J, Lurain Nell S, Ghazal Peter, Trivedi Urmi, Cunningham Charles, Baluchova Katarina, Gatherer Derek, Wilkinson Gavin W G, Dargan Derrick J, Davison Andrew J

Abstract excerpt

The genomes of commonly used variants of human cytomegalovirus (HCMV) strains Towne and AD169 each contain a substantial mutation in which a region (U(L)/b') at the right end of the long unique region has been replaced by an inverted duplication of a region from the left end of the genome. Using high-throughput technology, we have sequenced HCMV strain Towne (ATCC VR-977) and confirmed the presence of two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cytomegalovirus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytomegalovirus and herpesvirus research

Share to DNA, Viral

Share to IRS1 gene

Share to Genetic Variation

Share to Genome, Viral

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 19553388
DOI: 10.1099/vir.0.013250-0
PMCID: PMC2885757

Genes

IRS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169.PMID 19553388Read ↗

Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cellsSemantic proximity Read ↗

Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.Semantic proximity Read ↗

Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cellsSemantic proximity Read ↗

High-Throughput Analysis of Human Cytomegalovirus Genome Diversity Highlights the Widespread Occurrence of Gene-Disrupting Mutations and Pervasive RecombinationSemantic proximity Read ↗

Coding potential of laboratory and clinical strains of human cytomegalovirus.Semantic proximity Read ↗

Human Cytomegalovirus Genomes Sequenced Directly from Clinical Material: Variation, Multiple-Strain Infection, Recombination and MutationSemantic proximity Read ↗

Functional map of human cytomegalovirus AD169 defined by global mutational analysis.Semantic proximity Read ↗

Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights.Semantic proximity Read ↗

A review of genetic differences between limited and extensively passaged human cytomegalovirus strains.Semantic proximity Read ↗

Human cytomegalovirus: taking the strain.Semantic proximity Read ↗

Human Cytomegalovirus Genomes Sequenced Directly From Clinical Material: Variation, Multiple-Strain Infection, Recombination, and Gene LossSemantic proximity Read ↗

Molecular epidemiology of envelope glycoprotein H of human cytomegalovirus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.