Article
Identification of human ccn2 (connective tissue growth factor) promoter polymorphisms.
Molecular pathology : MP - 1 Jun 2001
Blom I E, van Dijk A J, de Weger R A, Tilanus M G, Goldschmeding R
Abstract excerpt
BACKGROUND: Connective tissue growth factor (CCN2; CTGF) is a newly identified growth factor, which is involved in the regulation of wound repair and fibrosis. Because there is variation among individuals with respect to tissue response to injury, genetic factors might be involved in the final outcome of tissue repair or scarring. For example, polymorphisms in the promoter region of genes, such as those encoding...
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