Article
Genetic variation in the promoter region of the basic fibroblast growth factor gene.
Human immunology - 1 Mar 2003
Beránek Michal, Tschöplová Svatava, Kanková Katerina, Kuhrová Vera, Vácha Jirí
Abstract excerpt
Basic fibroblast growth factor (bFGF) is a member of the fibroblast growth factor family that possess broad mitogenic and cell survival activities and is involved in a variety of biological processes. We investigated possible genetic polymorphism in the promoter and 5' flanking region of the bFGF gene. Polymorphism was analysed by means of heteroduplex analysis, fragments with altered mobility were sequenced....
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