Article
Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors.
Blood - 1 Jun 2001
McIlroy D, Troadec C, Grassi F, Samri A, Barrou B, Autran B, Debré P, Feuillard J, Hosmalin A
Abstract excerpt
Although the mouse spleen dendritic cell (DC) is perhaps the most intensively studied DC type, little has been published concerning its human equivalent. In this report, rare event flow cytometry and in situ immunofluorescence were used to study the surface phenotype and distribution of HLA-DR(+) CD3(-)14(-)16(-)19(-) human spleen DC. Spleens from organ donors with different clinical histories were used. Most...
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