Article
Characterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.
Clinical and vaccine immunology : CVI - 1 Sept 2006
Zhuang Yan, Mwangi Waithaka, Brown Wendy C, Davis William C, Hope Jayne C, Palmer Guy H
Abstract excerpt
Immature dendritic cells (DCs) resident in bovine spleens represent a distinct CD11a(+) CD11c(+) CD13(+) CD172(+) CD205(+) population compared to those circulating in peripheral blood or trafficking via afferent lymph. Upon cytokine-induced maturation, splenic DCs both efficiently present antigen in the stimulation of allogeneic lymphocyte proliferation and recall antigen-specific responses.
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