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Article

Plasmin-mediated release of the guidance molecule F-spondin from the extracellular matrix.

The Journal of biological chemistry - 27 Jul 2001

Tzarfaty-Majar V, López-Alemany R, Feinstein Y, Gombau L, Goldshmidt O, Soriano E, Muñoz-Cánoves P, Klar A

Abstract excerpt

Serine proteases are implicated in a variety of processes during neurogenesis, including cell migration, axon outgrowth, and synapse elimination. Tissue-type plasminogen activator and urokinase-type activator are expressed in the floor plate during embryonic development. F-spondin, a gene also expressed in the floor plate, encodes a secreted, extracellular matrix-attached protein that promotes outgrowth of...

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PMID: 11359777
DOI: 10.1074/jbc.M102585200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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