Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optimal sibship selection for genotyping in quantitative trait locus linkage analysis.

Human heredity - 1 Jan 2001

Purcell S, Cherny S S, Hewitt J K, Sham P C

Abstract excerpt

In this paper we present a novel method for selecting optimally informative sibships of any size for quantitative trait locus (QTL) linkage analysis. The method allocates a quantitative index of potential informativeness to each sibship on the basis of observed trait scores and an assumed true QTL model. Any sample of phenotypically screened sibships can therefore be easily rank-ordered for selective genotyping....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Genetic Linkage
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Genetic

Share to Nuclear Family

Share to Quantitative Trait, Heritable

Source

Identifiers

PMID: 11359064
DOI: 10.1159/000053350

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optimal sibship selection for genotyping in quantitative trait locus linkage analysis.PMID 11359064Read ↗

Optimal selection of sib pairs from random samples for linkage analysis of a QTL using the EDAC test.Semantic proximity Read ↗

Linkage analysis of quantitative trait loci: sib pairs or sibships?Semantic proximity Read ↗

Cost-effective sib-pair designs in the mapping of quantitative-trait loci.Semantic proximity Read ↗

A unified sampling approach for multipoint analysis of qualitative and quantitative traits in sib pairs.Semantic proximity Read ↗

Locating human quantitative trait loci: guidelines for the selection of sibling pairs for genotyping.Semantic proximity Read ↗

Sib mating designs for mapping quantitative trait loci.Semantic proximity Read ↗

Extreme discordant sib pairs for mapping quantitative trait loci in humans.Semantic proximity Read ↗

Mapping quantitative-trait loci in humans by use of extreme concordant sib pairs: selected sampling by parental phenotypes.Semantic proximity Read ↗

Novel sib pair selection strategy increases power in quantitative association analysis.Semantic proximity Read ↗

Fine mapping quantitative trait loci under selective phenotyping strategies based on linkage and linkage disequilibrium criteria.Semantic proximity Read ↗

Optimal allele-sharing statistics for genetic mapping using affected relatives.Semantic proximity Read ↗

Multipoint identity-by-descent prediction using dense markers to map quantitative trait loci and estimate effective population size.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.