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Article

Linkage analysis of quantitative trait loci: sib pairs or sibships?

Human heredity - 1 Jan 2000

Alcaïs A, Abel L

Abstract excerpt

Sib pair linkage studies are now widely used to investigate the genetic factors implicated in complex quantitative traits. To increase the power of these approaches, it has been proposed to select extremely discordant (ED) sib pairs which are expected to contain the highest linkage information. However, it is known that sibships of larger size contain more linkage information than independent sib pairs. In this...

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PMID: 10782019
DOI: 10.1159/000022925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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