Article
Population genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-175 (eba-175) gene.
Molecular and biochemical parasitology - 25 Apr 2001
Binks R H, Baum J, Oduola A M, Arnot D E, Babiker H A, Kremsner P G, Roper C, Greenwood B M, Conway D J
Abstract excerpt
The Plasmodium falciparum erythrocyte binding antigen-175 gene (eba-175) has highly divergent allelic segments (Cseg and Fseg) in one part of the gene (region III), but only a small number of single nucleotide polymorphisms (SNPs) in the rest of the sequence. Here, evidence for the possible importance of the Cseg/Fseg dimorphism was sought in a molecular population genetic analysis of the gene. First, allele...
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