Article
Genetic diversity of polymorphic vaccine candidate antigens (apical membrane antigen-1, merozoite surface protein-3, and erythrocyte binding antigen-175) in Plasmodium falciparum isolates from western and central Africa.
The American journal of tropical medicine and hygiene - 1 Feb 2011
Soulama Issiaka, Bigoga Jude D, Ndiaye Magatte, Bougouma Edith C, Quagraine Josephine, Casimiro Prisca N, Stedman Timothy T, Sirima Sodiomon B
Abstract excerpt
The malaria vaccine candidate antigens erythrocyte binding antigen 175 (EBA-175), merozoite surface protein 3 (MSP-3), and apical membrane antigen (AMA-1) from Plasmodium falciparum isolates from countries in central and west Africa were assessed for allelic diversity. Samples were collected on filter paper from 600 P. falciparum-infected symptomatic patients in Cameroon, Republic of Congo, Burkina Faso, Ghana,...
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