Article
Evolution of Fseg/Cseg dimorphism in region III of the Plasmodium falciparum eba-175 gene.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2017
Yasukochi Yoshiki, Naka Izumi, Patarapotikul Jintana, Hananantachai Hathairad, Ohashi Jun
Abstract excerpt
The 175-kDa erythrocyte binding antigen (EBA-175) of the malaria parasite Plasmodium falciparum is important for its invasion into human erythrocytes. The primary structure of eba-175 is divided into seven regions, namely I to VII. Region III contains highly divergent dimorphic segments, termed Fseg and Cseg. The allele frequencies of segmental dimorphism within a P. falciparum population have been extensively...
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