Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations at the APC exon 15 in the colorectal neoplastic tissues of serial array.

International journal of colorectal disease - 1 Apr 2001

Kim J C, Koo K H, Lee D H, Roh S A, Kim H C, Yu C S, Kang G H

Abstract excerpt

Although the APC protein is known to participate in cellular proliferation and apoptosis, APC mutations have been thought to play a major role in the early stage of colorectal tumorigenesis. The somatic APC mutation of exon 15 was assessed to determine its impact on various stages of colorectal tumorigenesis. The colorectal neoplastic tissues of serial array studied included sporadic adenomas (group 1, n = 36),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenoma
Share to Biopsy, Needle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Culture Techniques

Share to Genes, APC

Share to Multivariate Analysis

Share to Regression Analysis

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 11355315
DOI: 10.1007/s003840000283

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations at the APC exon 15 in the colorectal neoplastic tissues of serial array.PMID 11355315Read ↗

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene.Semantic proximity Read ↗

Genetic and epigenetic changes in the APC gene in sporadic colorectal carcinoma with synchronous adenoma.Semantic proximity Read ↗

Different familial adenomatous polyposis phenotypes resulting from deletions of the entire APC exon 15.Semantic proximity Read ↗

Novel strategies for comprehensive mutation screening of the APC gene.Semantic proximity Read ↗

Identical APC exon 15 mutations result in a variable phenotype in familial adenomatous polyposis.Semantic proximity Read ↗

Three novel mutations of APC gene in Chinese patients with familial adenomatous polyposis.Semantic proximity Read ↗

[Mutations of APC gene MCR region in sporadic colorectal adenomas and carcinomas].Semantic proximity Read ↗

Clinical characteristics and APC gene mutation spectrum of familial adenomatous polyposis patients in ChinaSemantic proximity Read ↗

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.Semantic proximity Read ↗

Characterization of APC exon 15 germ-line mutation in FAP family with severe phenotype showing extracolonic symptoms.Semantic proximity Read ↗

APC mutations in sporadic colorectal carcinomas from The Netherlands Cohort StudySemantic proximity Read ↗

Different phenotype manifestation of familial adenomatous polyposis in families with APC mutation at codon 1309.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.