Article

Clinical characteristics and APC gene mutation spectrum of familial adenomatous polyposis patients in China

2025-08-22

Abstract excerpt

<title>Abstract</title> <p>Purpose Given the limited clinical and molecular characterization of familial adenomatous polyposis (FAP) in Chinese populations, this study delineates the APC mutational landscape in national probands and correlates genotypic profiles with phenotypic manifestations. Methods Comprehensive APC gene sequencing was conducted in 33 unrelated Chinese polyposis patients, with subsequent genot...

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Literature Corpus work: ff8df987-caa7-58ca-976e-2eaffa3a87fa
DOI: 10.21203/rs.3.rs-7339521/v1

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